Catalysts accelerate chemical reactions that otherwise proceed
slowly. The enzyme called catalase is a catalyst. It exists in plant and animal cells and breaks down hydrogen
peroxide, H2O2, which is a byproduct of metabolism that is toxic if it accumulates in a cell.
Catalase, like most enzymes, is sensitive to the conditions in which it operates. Under favorable conditions, the reaction occurs very fast.
MVHS offers three activities that explore the effects of temperature and pH on enzyme reaction rates.
In the first activity, the students build a computer model in a programming language called
STELLATM. The enzyme reaction rate activity allows students to simulate the effects of
variables such as temperature and pH on the reaction rate of the enzyme catalase. This computer simulation
is best used after the students have done a wet lab experiment. The value of the simulation is that it
requires the students to interpret and analyze the graphical representation of data and it enables
the running of mutiple experiments in a short amount of time.
The second activity is a web-based simulation
derived from the STELLATM model above. The main factors that
influence enzyme-catalyzed reactions are temperature, pH, enzyme concentration, and substrate concentration.
The purpose of this simulation is to discover the optimal conditions for a fast reaction rate.
The third activity
provides a complete set of lessons for the teaching of enzyme reaction rates. Each module is organized
according to the 5E guidelines. In Module 3,
either activity described above may be used as the extension.